Launch HN: PostEra (YC W20) Medicinal Chemistry-as-a-Service and Covid Moonshot
Hey everyone! We’re Alpha, Matt and Aaron, co-founders of PostEra ( https://postera.ai/ ). The title above is quite a mouthful (we used all 80 characters) so we'll begin by breaking down what it means. What is medicinal chemistry? It’s part of discovering new drugs. A drug hunter decides what disease to focus on and then selects ‘targets’: usually proteins whose activity is key to the disease. Then they look for a molecule that can ‘hit’ that target and stimulate a response which will hopefully have beneficial effects. Developing such a molecule that is potent and safe is medicinal chemistry. Despite it being a crucial part of drug development, this field has relied on trial-and-error approaches—a very expensive way to muddle toward a drug. Where computational tools have been used, they have emphasized the 'best' designs without any awareness of what it would take to physically make the drug in a lab and test it. Our approach is to apply computational meth
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